10-Panel (Ten-Panel Drug Test)

An expanded drug test screening for ten substance categories, commonly used in non-DOT corporate drug-free workplace programs.

Key Facts

  • Includes all 5-panel substances plus 5 additional categories
  • Adds: benzodiazepines, barbiturates, methadone, propoxyphene, methaqualone
  • Not DOT-compliant — used for non-regulated workplace testing
  • Common in corporate drug-free workplace programs
  • Wider detection window for prescription drug abuse

The ten-panel drug test extends the standard 5-panel by adding five additional substance categories: benzodiazepines (Valium, Xanax), barbiturates, methadone, propoxyphene, and methaqualone. This panel is not DOT-compliant and is used primarily in non-regulated corporate drug-free workplace programs where employers want broader detection coverage. The 10-panel is popular in healthcare, financial services, and government employment where prescription drug misuse is a concern. Some employers further customize panels to include oxycodone, fentanyl, or other synthetic opioids.

Drug Testing Panels Compared

Breakdown of substances detected by common workplace drug testing panel configurations.

TypeSubstancesCommon UseDOT CompliantSpecimen Type
5-PanelTHC, Cocaine, Opiates, PCP, AmphetaminesDOT-mandated testingYesUrine or oral fluid
10-Panel5-panel + Benzos, Barbiturates, Methadone, Propoxyphene, MethaqualoneCorporate drug-free workplaceNo (expanded panel)Urine
Hair Follicle5–17+ substances (90-day window)Pre-employment, zero-tolerance policiesNoHair
Oral Fluid5–12+ substances (24–48 hr window)On-site, reasonable suspicionYes (since 2023)Saliva

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