Pre-employment screening in occupational health typically includes drug testing (DOT or non-DOT depending on role), physical examinations (DOT physical for CMV operators, OSHA-specific physicals for certain jobs), and health assessments to ensure the candidate can safely perform job duties. Under DOT regulations, a pre-employment drug test with a verified negative result must be obtained before a driver performs any safety-sensitive functions. Results must be received by the employer before the first day of safety-sensitive work. Pre-employment alcohol testing is permitted but optional under DOT.