Titer Test

A blood test that measures the concentration of antibodies to determine if a person has immunity to a specific disease.

Key Facts

  • Blood test measuring antibody concentration for a specific disease
  • Proves immunity without needing a new vaccination
  • Required for healthcare workers (Hep B, MMR, Varicella)
  • "Positive" titer means immune; "negative" means not immune

A titer test (also called an antibody titer) measures the level of antibodies in blood to determine immune status. In occupational health, titer tests are commonly used to verify immunity to measles, mumps, rubella (MMR), varicella (chickenpox), and hepatitis B when vaccination records are unavailable. Healthcare workers frequently need titer testing as part of onboarding or annual compliance. A "positive" or "immune" titer indicates sufficient antibody levels; a negative result may require vaccination or booster.

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